1) Visualization of biomolecular dynamics in cells [ Bioimaging ]
By using visualization technologies with high spatial resolution such as super-resolution fluorescence microscopes, the micro- to nano-structures of intracellular organelles can be observed. However, it is still ambiguous how various biomolecules actually move and function in living organelles. We are developing molecular probes that can visualize and clarify the local biomolecular dynamics and functions in living cells, specifically in organelles.
Ongoing research theme
2) Light manipulation of intracellular and in vivo molecular functions
[ Photopharmacology, Optochemical biology ]
3) Elucidation of protein function and development of new functional proteins
[ Bioinorganic chemistry, Protein engineering ]
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Research: Bioimaging