最近の論文

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原著論文 (Original Paper)

2020年

  1. Kashida, Hiromu; Azuma, Hidenori; Maruyama, Ryoko; Araki, Yasuyuki; Wada Takehiko; Asanuma, Hiroyuki,

Efficient Light-Harvesting Antennae Resulting from the Dense Organization of Dyes into DNA Junctions through D-Threoninol,

Angewandte Chemie, International Ed., 59, 11360-11363 (2020). (査読有)

  1. Ghidinelli, Simone; Abbate, Sergio; Koshoubu, Jun; Araki, Yasuyuki; Wada Takehiko; Longhi, Giovanna,

Solvent Effects and Aggregation Phenomena Studied by Vibrational Optical Activity and Molecular Dynamics: The Case of Pantolactone,

Journal of Physical Chemistry B, 124 (22), 4512-4526 (2020). (査読有) (査読有)

  1. Yospanya, Wijak; Nishijima, Masaki; Araki, Yasuyuki; Buffeteau, Thierry; Pouget, Emilie; Wada Takehiko; Oda, Reiko,

Near perfect head-to-head selectivity on the supramolecular photocyclodimerisation of 2-anthracenecarboxylate with self-organised gemini surfactant bilayers,

Chemical Communications, 56 (69), 10058-10061 (2020). (査読有) （東北大学・ボルドー大学からプレスリリース  ⇒ 日本経済新聞電子版・日本の研究 他掲載）

  1. Sekizawa, Yu; Mitomo, Hideyuki; Nihei, Mizuki; Nakamura, Satoshi; Yonamine, Yusuke; Kuzuya, Akinori; Wada Takehiko; Ijiro, Kuniharu,

Reversible changes in the orientation of gold nanorod arrays on polymer brushes,

Nanoscale Advances, 2, 3798-3803 (2020). (査読有) （Nanoscale Advances 誌表紙に採択）

  1. Chen, Bihai; Wada Takehiko; Yabu, Hiroshi,

Underwater Bubble and Oil Repellency of Biomimetic Pincushion and Plastron-Like Honeycomb Films,

Langmuir, 36, 6365-6369 (2020). (査読有) (Langmuir誌インサイドカバー表紙に採択)

  1. Masuda, Tsukuru; Hiraguchi, Yukari; Kushiro, Keiichiro; Araki, Yasuyuki; Wada Takehiko; Takai, Madoka,

Protein adsorption behavior in nanoscale phase-separated polymer coatings prepared using poly(2-methacrylolyoxyethyl phosphorylcholine) -containing amphiphilic block copolymers.

European Polymer Journal, 135, 109885 (2020). (査読有)

  1. Kashida, Hiromu; Kawai, Hayato; Azuma, Hidenori; Araki, Yasuyuki; Wada Takehiko Asanuma, Hiroyuki,

Quantitative Analyses of Foerster Resonance Energy Transfer between Identical Pyrene Chromophores (Homo-FRET) In DNA Scaffolds,

ChemPhotoChem, 5, 167-172 (2020). (査読有)

著書・解説・資料等

  1. 核酸科学ハンドブック　日本核酸化学会監修　杉本直己編　　総ページ数：576頁

第7章　「人工核酸高分子の合成」

和田健彦, PP 209-221, (株)講談社　2020　(査読有　著書)

2019年

  1. Development of an Engineered Photoactive Yellow Protein as a Cross-Linking Junction for Construction of Photoresponsive Protein-Polymer Conjugates

Ui, Mihoko; Miyauchi, Yusuke; Inoue, Masataka; Murakami, Makoto; Araki, Yasuyuki; Wada, Takehiko; Kinbara, Kazushi

ChemPhotoChem., 3, 262-268 (2019). (査読有)

  1. N-Benzoyl-Protected Peptide Nucleic Acid (PNA) Monomers Expand the Range of Nucleobases Available for PNA-DNA Chimera,

Masahito Inagaki , Ryohei Uematsu , Tatsuya Mizutani , Daisuke Unabara, Yasuyuki Araki , Seiji Sakamoto , Hiromu Kashida , Masaki Nishijima , Hiroyuki Asanuma , Yoshihisa Inoue , and Takehiko Wada*

Chemistry Letters, 48, 341-344 (2019). (査読有)

 

  1. Transient Circular Dichroism Measurement of The Excited Triplet State of Pristine Hexahelicene in Solution at Room Temperature,

Makoto Kuronuma , Takehito Sato , Yasuyuki Araki , Tadashi Mori , Seiji Sakamoto, Yoshihisa Inoue , Osamu Ito , and Takehiko Wada*

Chemistry Letters, 48, 357-360 (2019). (査読有)

 

著書・解説・資料等

ヌクレアーゼ活性向上を指向したDNA-人工核酸キメラ分子構造設計と新機能創製,

稲垣雅仁、和田健彦

日本化学会生体機能関連化学部会NEWS LETTER, 34, 4-6 (2019). (査読有　日本語論文)

 

2018年

  1. Development of an Engineered Photoactive Yellow Protein as a Cross-Linking Junction for Construction of Photoresponsive Protein-Polymer Conjugates

Ui, Mihoko; Miyauchi, Yusuke; Inoue, Masataka; Murakami, Makoto; Araki, Yasuyuki; Wada, Takehiko; Kinbara, Kazushi

ChemPhotoChem., 2 (2018) in press: DOI: 10.1002/cptc.201900024 (査読有)

 

  1. Quantitative evaluation of energy migration between identical chromophores enabled by breaking symmetry,

Hiromu Kashida, Hayato Kawai, Ryoko Maruyama, Yuta Kokubo, Yasuyuki Araki, Takehiko Wada, Hiroyuki Asanuma

Communications Chemistry (Nature), 1, 91-98 (2018): 10.1038/s42004-018-0093-0　(査読有)

 

  1. Concentration-dependent photophysical switching in mixed self-assembled monolayers of pentacene and perylenediimide on gold nanoclusters

Kato, Daiki; Sakai, Hayato; Araki, Yasuyuki; Wada, Takehiko; Tkachenko, Nikolai V.; Hasobe, Taku

Physical Chemistry Chemical Physics, 20 (13), 8695-8706 (2018): DOI: 10.1039/C8CP00174J　(査読有)

 

  1. Circular Polarized Luminescence of Hydrogen-Bonded Molecular Assemblies of Chiral Pyrene Derivatives

Anetai, Hayato; Takeda, Takashi; Hoshino, Norihisa; Araki, Yasuyuki; Wada, Takehiko; Yamamoto, Shunsuke; Mitsuishi, Masaya; Tsuchida, Hiromu; Ogoshi, Tomoki; Akutagawa, Tomoyuki

Journal of Physical Chemistry C, 122 (11), 6323-6331 (2018): DOI: 10.1021/acs.jpcc.7b12747　(査読有)

 

  1. Peptide ribonucleic acid (PRNA)-arginine hybrids. effects of arginine residues alternatingly introduced to PRNA backbone on aggregation, cellular uptake, and cytotoxicity

Sugai, Hiroka; Nakase, Ikuhiko; Sakamoto, Seiji; Nishio, Akihiro; Inagaki, Masahito; Nishijima, Masaki; Yamayoshi, Asako; Araki, Yasuyuki; Ishibashi, Satoru; Yokota, Takanori; Inoue, Yoshihisa; Wada, Takehiko

Chemistry Letters, 47 (3), 381-384 (2018): DOI: 10.1246/cl.171186. (査読有)


  1. Fabrication of protein nanoassemblies composed of engineered split-CFP and split-YFP,

Sakamoto, Seiji; Hugo, Anna; Terauchi, Mika; Araki, Yasuyuki; Wada, Takehiko

Peptide Science, 53, 301-302 (2018). (査読有)

 

著書・解説・資料等

ヌクレアーゼ活性向上を指向したDNA-人工核酸キメラ分子構造設計と新機能創製,

稲垣雅仁、和田健彦

日本化学会生体機能関連化学部会NEWS LETTER, 33 (3), 4-6 (2018). (査読有　日本語論文)

 

光とタンパク質を活用したキラル化合物合成法:生体高分子をキラル反応場として活用した超分子不斉光反応系の創成 －環境調和型不斉合成法の開発を目指して－

和田健彦、荒木保幸、西嶋政樹, 光アライアンス, 23 (6), 6-11 (2018). (査読有　日本語論文)

 

刺激応答性高分子ハンドブック　宮田隆志　編　総ページ数：864頁

基礎編　第２章 合成・設計　第30節 刺激応答性人工核酸の設計と機能

和田健彦, PP 146-152, (株)エヌ・ティー・エス　　2018.12.18.(査読有　著書)

ISBN: 978-4-86043-535-6 C3043

2017年

1． Protonation-induced red-coloured circularly polarized luminescence of [5]carbohelicene fused by benzimidazole

By Sakai, Hayato; Kubota, Takako; Yuasa, Junpei; Araki, Yasuyuki; Sakanoue, Tomo; Takenobu, Taishi; Wada, Takehiko; Kawai, Tsuyoshi; Hasobe, Taku

From Organic & Biomolecular Chemistry (2016), 14(28), 6738-6743. Language: English, Database: CAPLUS, DOI:10.1039/C6OB00937A：　(査読有)　IF=3.559

 

  1. Controllable Electronic Structures and Photoinduced Processes of Bay-Linked Perylenediimide Dimers and a Ferrocene-Linked Triad

By Horinouchi, Haruki; Sakai, Hayato; Araki, Yasuyuki; Sakanoue, Tomo; Takenobu, Taishi; Wada, Takehiko; Tkachenko, Nikolai V.; Hasobe, Taku

From Chemistry – A European Journal (2016), 22(28), 9631-9641. Language: English, Database: CAPLUS, DOI:10.1002/chem.201601058：(査読有) IF=5.771

 

  1. Activation of p53 facilitates the target search in DNA by enhancing the target recognition probability

By Itoh, Yuji; Murata, Agato; Sakamoto, Seiji; Nanatani, Kei; Wada, Takehiko; Takahashi, Satoshi; Kamagata, Kiyoto

From Journal of Molecular Biology (2016), 428(14), 2916-2930. Language: English, Database: CAPLUS, DOI:10.1016/j.jmb.2016.06.001：(査読有)　IF=4.632

 

  1. General review for supramolecular photochirogenesis

By Mori, Tadashi; Fukuhara, Gaku; Wada, Takehiko

From Journal of Photochemistry and Photobiology, A: Chemistry (2016), 331, 2-7. Language: English, Database: CAPLUS, DOI:10.1016/j.jphotochem.2016.08.006：(査読有)　IF=2.477

 

  1. Synthetic Control of Photophysical Process and Circularly Polarized Luminescence of [5]Carbohelicene Derivatives Substituted by Maleimide Units

By Sakai, Hayato; Kubota, Takako; Yuasa, Junpei; Araki, Yasuyuki; Sakanoue, Tomo; Takenobu, Taishi; Wada, Takehiko; Kawai, Tsuyoshi; Hasobe, Taku

From Journal of Physical Chemistry C (2016), 120(14), 7860-7869. Language: English, Database: CAPLUS, DOI:10.1021/acs.jpcc.6b01344：(査読有) IF=4.506

 

  1. Controlled Excited-State Dynamics and Enhanced Fluorescence Property of Tetrasulfone[9]helicene by a Simple Synthetic Process

By Yamamoto, Yuki; Sakai, Hayato; Yuasa, Junpei; Araki, Yasuyuki; Wada, Takehiko; Sakanoue, Tomo; Takenobu, Taishi; Kawai, Tsuyoshi; Hasobe, Taku

From Journal of Physical Chemistry C (2016), 120(13), 7421-7427. Language: English, Database: CAPLUS, DOI:10.1021/acs.jpcc.6b01123：(査読有) IF=4.506

 

  1. Long-lived triplet excited states of bent-shaped pentacene dimers by intramolecular singlet fission

By Sakuma, Takao; Sakai, Hayato; Araki, Yasuyuki; Mori, Tadashi; Wada, Takehiko; Tkachenko, Nikolai V.; Hasobe, Taku

From Journal of Physical Chemistry A (2016), 120(11), 1867-1875. Language: English, Database: CAPLUS, DOI:10.1021/acs.jpca.6b00988：(査読有)　IF=2.883

 

  1. The themed issue in honor of Prof. Yoshihisa Inoue for his contribution on molecular and supramolecular photochemistry

By Mori, Tadashi; Fukuhara, Gaku; Wada, Takehiko

From Journal of Photochemistry and Photobiology, A: Chemistry (2016), 331, 1. Language: English, Database: CAPLUS, DOI:10.1016/j.jphotochem.2016.09.029：　(査読有) 　IF=2.477

 

  1. Synthetic Control of the Excited-State Dynamics and Circularly Polarized Luminescence of Fluorescent “Push-Pull” Tetrathia[9]helicenes

By Yamamoto, Yuki; Sakai, Hayato; Yuasa, Junpei; Araki, Yasuyuki; Wada, Takehiko; Sakanoue, Tomo; Takenobu, Taishi; Kawai, Tsuyoshi; Hasobe, Taku

From Chemistry – A European Journal (2016), 22(12), 4263-4273. Language: English, Database: CAPLUS, DOI:10.1002/chem.201504048：(査読有) IF=5.771

 

  1. Control of local structures and photophysical properties of zinc porphyrin-based supramolecular assemblies structurally organized by regioselective ligand coordination

By Sakuma, Takao; Sakai, Hayato; Araki, Yasuyuki; Wada, Takehiko; Hasobe, Taku

From Physical Chemistry Chemical Physics (2016), 18(7), 5453-5463. Language: English, Database: CAPLUS, DOI:10.1039/C5CP07110K：(査読有) IF=4.123

 

  1. Highly enantiodifferentiating site of human serum albumin for mediating photocyclodimerization of 2-anthracenecarboxylate elucidated by site-specific inhibition/quenching with xenon

By Nishijima, Masaki; Pace, Tamara C. S.; Bohne, Cornelia; Mori, Tadashi; Inoue, Yoshihisa; Wada, Takehiko

From Journal of Photochemistry and Photobiology, A: Chemistry (2016), 331, 89-94. Language: English, Database: CAPLUS, DOI:10.1016/j.jphotochem.2015.12.019：(査読有) IF=2.477

 

  1. Module strategy for peptide ribonucleic acid (PRNA)-DNA and PRNA-peptide nucleic acid (PNA)-DNA chimeras: synthesis and interaction of chimeras with DNA and RNA

By Uematsu, Ryohei; Inagaki, Masahito; Asai, Mitsuo; Sugai, Hiroka; Maeda, Yoshiki; Nagami, Akira; Sato, Hirofumi; Sakamoto, Seiji; Araki, Yasuyuki; Nishijima, Masaki; Wada, Takehiko

From Chemistry Letters (2016), 45(3), 350-352. Language: English, Database: CAPLUS, DOI:10.1246/cl.151157：　(査読有) IF=1.20

 

著書・解説・資料

和田健彦, 外部刺激応答型機能性水溶性機能高分子の新展開‐細胞内環境応答型核酸医薬の創製−, 高分子, 65, 416-419 (2016). (査読有）

 

和田健彦, 日本的思考に基づく新しいケミカルバイオロジー概念提案の勧め, 生命化学研究会レター, 52, 2-3 (2016). (査読有）

 

和田健彦, 細胞内環境応答性ペプチドリボ核酸, 和田猛監修「核酸医薬の創製と応用展開」, シーエムシー出版（東京）, 96-103 (2016). (査読有)

2015年

203. Nishijima, Masaki; Pace, Tamara C. S.; Bohne, Cornelia; Mori, Tadashi; Inoue, Yoshihisa; Wada, Takehiko,
“Highly enantiodifferentiating site of human serum albumin for mediating photocyclodimerization of 2-anthracenecarboxylate elucidated by site-specific inhibition/quenching with xenon”,
J. Photochem. Photobiol., A, in press. (DOI: 10.1016/j.jphotochem.2015.12.019)

202. Doi, Tetsuya; Sakakibara, Takumi; Kashida, Hiromu; Araki, Yasuyuki; Wada, Takehiko; Asanuma, Hiroyuki,
“Hetero-Selective DNA-Like Duplex Stabilized by Donor-Acceptor Interactions”,
Chem. – Eur. J., 21, 15974-15980 (2015). (DOI: 10.1002/chem.201502653)

201. Sakai, Hayato; Shinto, Sho; Kumar, Jatish; Araki, Yasuyuki; Sakanoue, Tomo; Takenobu, Taishi; Wada, Takehiko; Kawai, Tsuyoshi; Hasobe, Taku,
“Highly Fluorescent [7]Carbohelicene Fused by Asymmetric 1,2-Dialkyl-Substituted Quinoxaline for Circularly Polarized Luminescence and Electroluminescence”,
J. Phys. Chem. C, 119, 13937-13947 (2015). (DOI: 10.1021/acs.jpcc.5b03386)

200. Watanabe, Satoshi; Kawashima, Takumi; Nishitani, Yuichi; Kanai, Tamotsu; Wada, Takehiko; Inaba, Kenji; Atomi, Haruyuki; Imanaka, Tadayuki; Miki, Kunio,
“Structural basis of a Ni acquisition cycle for [NiFe] hydrogenase by Ni-metallochaperone HypA and its enhancer”,
Proc. Natl. Acad. Sci. USA., 112, 7701-7706 (2015). (DOI: 10.1073/pnas.1503102112)

2014年

199. Nishijima, Masaki; Goto, Masato; Fujikawa, Mayu; Yang, Cheng; Mori, Tadashi; Wada, Takehiko; Inoue, Yoshihisa,
“Mammalian serum albumins as a chiral mediator library for bio-supramolecular photochirogenesis: optimizing enantiodifferentiating photocyclodimerization of 2-anthracenecarboxylate”,
Chem. Commun., 50, 14082-14085 (2014). (DOI: 10.1039/c4cc04818k)

198. Sakai, Hayato; Shinto, Sho; Araki, Yasuyuki; Wada, Takehiko; Sakanoue, Tomo; Takenobu, Taishi; Hasobe, Taku,
“Formation of One-Dimensional Helical Columns and Excimerlike Excited States by Racemic Quinoxaline-Fused [7]Carbohelicenes in the Crystal”,
Chem. – Eur. J., 20, 10099-10109 (2014). (DOI: 10.1002/chem.201402426)

197. Fukuhara, Gaku; Umehara, Hiroaki; Higashino, Saki; Nishijima, Masaki; Yang, Cheng; Mori, Tadashi; Wada, Takehiko; Inoue, Yoshihisa,
“Supramolecular photocyclodimerization of 2-hydroxyanthracene with chiral hydrogen-bonding template, cyclodextrin and serum albumin”,
Photochem. Photobiol. Sci., 13, 162-171 (2014). (DOI: 10.1039/c3pp50127b)

196. Hirayama, Sunao; Sakai, Hayato; Araki, Yasuyuki; Tanaka, Minako; Imakawa, Masaki; Wada, Takehiko; Takenobu, Taishi; Hasobe, Taku,
“Systematic Control of the Excited-State Dynamics and Carrier-Transport Properties of Functionalized Benzo[ghi]perylene and Coronene Derivatives”,
Chem. – Eur. J., 20, 9081-9093 (2014) (DOI: 10.1002/chem.201304679)

195. Miyahara, Tomoo; Nakatsuji, Hiroshi; Wada, Takehiko,
“Circular Dichroism Spectra of Uridine Derivatives: ChiraSac Study”,
J. Phys. Chem. A, 118, 2931-2941 (2014). (DOI: 10.1021/jp501906u)

194. Ida, Koichi; Sakai, Hayato; Ohkubo, Kei; Araki, Yasuyuki; Wada, Takehiko; Sakanoue, Tomo; Takenobu, Taishi; Fukuzumi, Shunichi; Hasobe, Taku,
“Electron-Transfer Reduction Properties and Excited-State Dynamics of Benzo[ghi]peryleneimide and Coroneneimide Derivatives”,
J. Phys. Chem. C, 118, 7710-7720 (2014). (DOI: 10.1021/jp500761f)

193. Shinozaki, Yoshinao; Yoshikawa, Isao; Araki, Koji; Ohara, Kazuaki; Yamaguchi, Kentaro; Kawano, Shin-ichiro; Tanaka, Kentaro; Araki, Yasuyuki; Wada, Takehiko; Otsuki, Joe,
“Coordination oligomers and polymers of an oxazole-appended zinc chlorophyll derivative”,
Chem. Lett., 43, 862-864 (2014). (DOI: 10.1246/cl.140135)

192. Sakamoto, Seiji; Araki, Yasuyuki; Wada, Takehiko,
“Design of protease-activable cyclic peptide nucleic acid”,
Pept. Sci., 51, 287-288 (2014).

2013年

191. Sakamoto, Seiji; Terauchi, Mika; Hugo, Anna; Kim, Tanner; Araki, Yasuyuki; Wada, Takehiko,
“Creation of a caspase-3 sensing system using a combination of split-GFP and split-intein”,
Chem. Commun., 49, 10323-10325 (2013). (DOI: 10.1039/c3cc43389g)

190. Sakamoto, Seiji; Terauchi, Mika; Araki, Yasuyuki; Wada, Takehiko,
“Design and semisynthesis of photoactivable split-GFP by incorporation of photocleavable functionality”,
Biopolymers, 100, 773-779 (2013). (DOI: 10.1002/bip.22304)

189. Aiba, Yuichiro; Hamano, Yuya; Kameshima, Wataru; Araki, Yasuyuki; Wada, Takehiko; Accetta, Alessandro; Sforza, Stefano; Corradini, Roberto; Marchelli, Rosangela; Komiyama, Makoto,
“PNA-NLS conjugates as single-molecular activators of target sites in double-stranded DNA for site-selective scission”,
Org. Biomol. Chem., 11, 5233-5238 (2013). (DOI: 10.1039/c3ob40947c)

188. Nishijima, Masaki; Kato, Hanako; Yang, Cheng; Fukuhara, Gaku; Mori, Tadashi; Araki, Yasuyuki; Wada, Takehiko; Inoue, Yoshihisa,
“Catalytic Bio-Supramolecular Photochirogenesis: Batch-Operated Enantiodifferentiating Photocyclodimerization of 2-Anthracenecarboxylate with Human Serum Albumin”,
ChemCatChem, 5, 3237-3240 (2013). (DOI: 10.1002/cctc.201300160)

187. Shinozaki, Yoshinao; Richards, Gary; Ogawa, Keizo; Yamano, Akihito; Ohara, Kazuaki; Yamaguchi, Kentaro; Kawano, Shin-ichiro; Tanaka, Kentaro; Araki, Yasuyuki; Wada, Takehiko; Otsuki, Joe,
“Double Helices of a Pyridine-Appended Zinc Chlorophyll Derivative”,
J. Am. Chem. Soc., 135, 5262-5265 (2013). (DOI: 10.1021/ja400493e)

186. Murakami, Makoto; Araki, Yasuyuki; Sakamoto, Seiji; Hamada, Yoshiki; Wada, Takehiko,
“Remarkable enhancement of sensitivity with the second generation of elliptically polarization-detected circular dichroism spectroscopy”,
Chem. Lett., 42, 261-262 (2013). (DOI: 10.1246/cl.2013.261)

185. Sakamoto, Seiji; Hugo, Anna; Terauchi, Mika; Araki, Yasuyuki; Wada, Takehiko,
“Design of a sensing system for caspase-3 activities using a combination of split-luciferase and split-intein”,
Pept. Sci., 50, 387-388 (2013).

184. Sakamoto, Seiji; Hugo, Anna; Terauchi, Mika; Araki, Yasuyuki; Wada, Takehiko,
“Design and preparation of a dual-protease biosensor for two different caspase activities using split-GFP”,
Pept. Sci., 49, 283-284 (2013).

2012年

183. Nishiyama, Yasuhiro; Wada, Takehiko; Kakiuchi, Kiyomi; Inoue, Yoshihisa,
“Entrainer Effects on Enantiodifferentiating Photocyclization of 5-Hydroxy-1, 1-diphenylpentene in Near-Critical and Supercritical Carbon Dioxide”,
J. Org. Chem., 77, 5681-5686 (2012). (DOI: 10.1021/jo300816w)

182. Nishiyama, Yasuhiro; Wada, Takehiko; Kakiuchi, Kiyomi; Inoue, Yoshihisa,
“Microenvironmental Control of Enantiodifferentiating Photocyclization of 5-Hydroxy-1,1-diphenylpentene through Selective Solvation”,
Chirality, 24, 400-405 (2012). (DOI: 10.1002/chir.22004)

181. Ui, Mihoko; Tanaka, Yoshikazu; Araki, Yasuyuki; Wada, Takehiko; Takei, Toshiaki; Tsumoto, Kouhei; Endo, Sumire; Kinbara, Kazushi,
“Application of photoactive yellow protein as a photoresponsive module for controlling hemolytic activity of staphylococcal α-hemolysin”,
Chem. Commun., 48, 4737-4739 (2012). (DOI: 10.1039/c2cc18118e)

180. Wada, Takehiko,
“New paradigm of biomolecular soft-interfaces as chiral reaction fields for supramolecular asymmetric photochirogenesis”,
Hyomen Kagaku, 33, 27-33 (2012). (DOI: 10.1380/jsssj.33.27)

179. Sakamoto, Seiji; Terauchi, Mika; Taki, Shusaku; Kim, Tanner Ian; Araki, Yasuyuki; Wada, Takehiko,
“Design of a dual-color detection system for caspase activities using a combination of split-fluorescent proteins and split-intein”,
Pept. Sci., 48, 325-326 (2012).

2011年

178. Wada, Takehiko; Nishijima, Masaki; Sakamoto, Seiji; Murakami, Makoto; Sugawara, Yui; Araki, Yasuyuki; Inoue, Yoshihisa,
“Novel strategy of supramolecular asymmetric photochirogenesis with tailor-made biopolymers as chiral reaction fields”,
J. Photopolym. Sci. Technol., 24, 595-596 (2011). (DOI: 10.2494/photopolymer.24.595)

177. Maeda, Ryo; Wada, Takehiko; Mori, Tadashi; Kono, Shigeyuki; Kanomata, Nobuhiro; Inoue, Yoshihisa,
“Planar-to-Planar Chirality Transfer in the Excited State. Enantiodifferentiating Photoisomerization of Cyclooctenes Sensitized by Planar-Chiral Paracyclophane”,
J. Am. Chem. Soc., 133, 10379-10381 (2011). (DOI: 10.1021/ja203781f)

176. Maeda, Ryo; Wada, Takehiko; Kusaka, Atsushi; Mori, Tadashi; Iwamoto, Masakazu; Inoue, Yoshihisa,
“Role of entropy in supramolecular photochirogenesis: enantiodifferentiating photoisomerization of cyclooctenes in chiral sensitizer-immobilized MCM-41 cavities”,
Photochem. Photobiol. Sci., 10, 1390-1392 (2011). (DOI: 10.1039/c1pp05087g)

175. Wada, Takehiko; Araki, Yasuyuki; Sakamoto, Seiji,
“Design and synthesis of artificial nucleic acid and non-natural protein for active control of cellular function and development of CD measurement system with high sensitive & high time resolution”,
Mater. Integr., 24, 10-16 (2011).

2010年

174. Tsutsumi, Ken; Yanagisawa, Yuuki; Furutani, Akinori; Morimoto, Tsumoru; Kakiuchi, Kiyomi; Wada, Takehiko; Mori, Tadashi; Inoue, Yoshihisa,
“Diastereodifferentiating the [2+2] Photocycloaddition of Ethylene to Arylmenthyl Cyclohexenonecarboxylates: Stacking-Driven Enhancement of the Product Diastereoselectivity That Is Correlated with the Reactant Ellipticity”,
Chem. – Eur. J., 16, 7448-7455 (2010). (DOI: 10.1002/chem.201000429)

173. Bando, Kazuki; Zako, Tamotsu; Sakono, Masafumi; Maeda, Mizuo; Wada, Takehiko; Nishijima, Masaki; Fukuhara, Gaku; Yang, Cheng; Mori, Tadashi; Pace, Tamara C. S.; Bohne, Cornelia; Inoue, Yoshihisa,
“Bio-supramolecular photochirogenesis with molecular chaperone: enantiodifferentiating photocyclodimerization of 2-anthracenecarboxylate mediated by prefoldin”,
Photochem. Photobiol. Sci., 9, 655-660 (2010). (DOI: 10.1039/b9pp00186g)

172. Song, Shi-Hui; Shirasaka, Kazumi; Hirokawa, Yasuhito; Asanuma, Hiroyuki; Wada, Takehiko; Sumaoka, Jun; Komiyama, Makoto,
“Molecular imprinting of cyclodextrin to physiologically active oligopeptides in water”,
Supramol. Chem., 22, 149-155 (2010). (DOI: 10.1080/10610270902980622)

171. Wada, Takehiko; Sawa, Nobuya; Sato, Hirofumi; Kikkawa, Mayuko; Onodera, Keiko; Sakamoto, Seiji; Inoue, Yoshihisa,
“Active control by external factors of DNA recognition behavior of α-peptide ribonucleic acids containing basic amino acid residues”,
Chem. Lett., 39, 112-113 (2010). (Editor’s Choice)  (DOI: 10.1246/cl.2010.112)

170. Nikawa, Hidefumi; Araki, Yasuyuki; Slanina, Zdenek; Tsuchiya, Takahiro; Akasaka, Takeshi; Wada, Takehiko; Ito, Osamu; Dinse, Klaus-Peter; Ata, Masafumi; Kato, Tatsuhisa; Nagase, Shigeru,
“The effect of atomic nitrogen on the C60 cage”,
Chem. Commun., 46, 631-633 (2010). (DOI: 10.1039/b914624e)

169. Sawa, Nobuya; Wada, Takehiko; Inoue, Yoshihisa,
“Synthesis and DNA-recognition behavior of a novel peptide ribonucleic acid with a serine backbone (oxa-PRNA)”,
Tetrahedron, 66, 344-349 (2010). (DOI: 10.1016/j.tet.2009.10.094)

168. Sawa, Nobuya; Sakamoto, Seiji; Yang, Cheng; Fukuhara, Gaku; Mori, Tadashi; Inoue, Yoshihisa; Wada, Takehiko,
“Synthesis, properties and complexation behavior of positively charged peptide ribonucleic acids with amino linkages in the backbone structure (aza-PRNA)”,
Pept. Sci., 321-324 (2010).

167. Sakamoto, Seiji; Terauchi, Mika; Kim, Tanner Ian; Araki, Yasuyuki; Wada, Takehiko,
“Design of a sensing system for caspase-3 activities using a combination of split-GFP and split-intein”,
Pept. Sci., 224 (2010).

166. Sakamoto, Seiji; Terauchi, Mika; Araki, Yasuyuki; Wada, Takehiko,
“Design and preparation of split-GFP for sensing of caspase-3 activities”,
Pept. Sci., 343-344 (2010).

2009年

165. Harada, Takashi; Hasegawa, Yasuchika; Nakano, Yoko; Fujiki, Michiya; Naito, Masanobu; Wada, Takehiko; Inoue, Yoshihisa; Kawai, Tsuyoshi,
“Circularly polarized luminescence from chiral Eu(III) Complex with high emission quantum yield”,
J. Alloys Compd., 488, 599-602 (2009). (DOI: 10.1016/j.jallcom.2008.09.100)

164. Kawanami, Yuko; Pace, Tamara C. S.; Mizoguchi, Jun-ichi; Yanagi, Toshiharu; Nishijima, Masaki; Mori, Tadashi; Wada, Takehiko; Bohne, Cornelia; Inoue, Yoshihisa,
“Supramolecular complexation and enantiodifferentiating photocyclodimerization of 2-anthracenecarboxylic acid with 4-aminoprolinol derivatives as chiral hydrogen-bonding templates”,
J. Org. Chem., 74, 7908-7921 (2009). (DOI: 10.1021/jo901792t)

163. Nishio, Akihiro; Sawa, Nobuya; Onodera, Keiko; Sakamoto, Seiji; Araki, Yasuyuki; Nakase, Ikuhiko; Futaki, Shiroh; Inoue, Yoshihisa; Wada, Takehiko,
“Studies on the effects of arginine residues introduced to peptide ribonucleic acids (PRNA) on the complex stability with RNA”,
Nucleic Acids Symp. Ser., 53, 55-56 (2009). (DOI: 10.1093/nass/nrp028)

162. Ke, Chenfeng; Yang, Cheng; Mori, Tadashi; Wada, Takehiko; Liu, Yu; Inoue, Yoshihisa,
“Catalytic Enantiodifferentiating Photocyclodimerization of 2-Anthracenecarboxylic Acid Mediated by a Non-Sensitizing Chiral Metallosupramolecular Host”,
Angew. Chem., Int. Ed., 48, 6675-6677 (2009). (DOI: 10.1002/anie.200902911)

161. Pace, Tamara C. S.; Nishijima, Masaki; Wada, Takehiko; Inoue, Yoshihisa; Bohne, Cornelia,
“Photophysical Studies on the Supramolecular Photochirogenesis for the Photocyclodimerization of 2-Anthracenecarboxylate within Human Serum Albumin”,
J. Phys. Chem. B, 113, 10445-10453 (2009). (DOI: 10.1021/jp903955f)

160. Xiao, Debao; Wada, Takehiko; Inoue, Yoshihisa,
“Supramolecular enantiodifferentiating photoisomerization of (Z)-cyclooctene in lyotropic and thermotropic liquid crystals”,
Chirality, 21, 110-113 (2009). (DOI: 10.1002/chir.20617)

159. Umeyama, Tomokazu; Takamatsu, Takeshi; Tezuka, Noriyasu; Matano, Yoshihiro; Araki, Yasuyuki; Wada, Takehiko; Yoshikawa, Osamu; Sagawa, Takashi; Yoshikawa, Susumu; Imahori, Hiroshi,
“Synthesis and Photophysical and Photovoltaic Properties of Porphyrin-Furan and -Thiophene Alternating Copolymers”,
J. Phys. Chem. C, 113, 10798-10806 (2009). (DOI: 10.1021/jp902001z)

158. Nishijima, Masaki; Wada, Takehiko; Nagamori, Koushi; Inoue, Yoshihisa,
“High-sensitivity HPLC quantification of nonfluorescent but photolabile analyte through photoreversion in fluorescence detector”,
Chem. Lett., 38, 726-727 (2009). (DOI: 10.1246/cl.2009.726)

157. Ito, Shinya; Araki, Yasuyuki; Tanaka, Atsunari; Igarashi, Jotaro; Wada, Takehiko; Shimizu, Toru,
“Role of Phe113 at the distal side of the heme domain of an oxygen-sensor (Ec DOS) in the characterization of the heme environment”,
J. Inorg. Biochem., 103, 989-996 (2009). (DOI: 10.1016/j.jinorgbio.2009.04.009)

156. Sakamoto, Seiji; Araki, Yasuyuki; Wada, Takehiko,
“Design of photoactivable split-GFP by incorporation of a photolabile linker”,
Pept. Sci., 487-490 (2009).

2008年

155. Nishiyama, Yasuhiro; Wada, Takehiko; Asaoka, Sadayuki; Mori, Tadashi; McCarty, Taylor A.; Kraut, Nadine D.; Bright, Frank V.; Inoue, Yoshihisa,
“Entrainer Effect on Photochirogenesis in Near- and Supercritical Carbon Dioxide: Dramatic Enhancement of Enantioselectivity”,
J. Am. Chem. Soc., 130, 7526-7527 (2008). (DOI: 10.1021/ja801254z)

154 Lu, Runhua; Yang, Cheng; Cao, Yujuan; Tong, Linhui; Jiao, Wei; Wada, Takehiko; Wang, Zhizhong; Mori, Tadashi; Inoue, Yoshihisa,
“Enantiodifferentiating Photoisomerization of Cyclooctene Included and Sensitized by Aroyl-beta-cyclodextrins: A Critical Enantioselectivity Control by Substituents”,
J. Org. Chem., 73, 7695-7701 (2008). (DOI: 10.1021/jo801439n)

153. Sandanayaka, Atula S. D.; Araki, Yasuyuki; Wada, Takehiko; Hasobe, Taku,
“Structural and Photophysical Properties of Self-Assembled Porphyrin Nanoassemblies Organized by Ethylene Glycol Derivatives”,
J. Phys. Chem. C, 112, 19209-19216 (2008). (DOI: 10.1021/jp805202y)

152. Xiao, Debao; Wada, Takehiko; Inoue, Yoshihisa,
“Supramolecular enantiodifferentiating photoisomerization of (Z)-cyclooctene in lyotropic and thermotropic liquid crystals”,
Chirality, 21, 110-113 (2008). (DOI: 10.1002/chir.20617)

152. Fukuhara, Gaku; Klaerner, Frank-Gerrit; Mori, Tadashi; Wada, Takehiko; Inoue, Yoshihisa, “Supramolecular complexation and photochirogenesis with inherently chiral molecular clip: enantiodifferentiating photoisomerization of (Z,Z)-1,3-cyclooctadiene and polar photoaddition to 1,1-diphenylpropene”,
Photochem. Photobiol. Sci., 7, 1493-1500 (2008). (DOI: 10.1039/B812186A)

150. Hasobe, Taku; Sandanayaka, Atula S. D.; Wada, Takehiko; Araki, Yasuyuki,
“Fullerene-encapsulated porphyrin hexagonal nanorods. An anisotropic donor-acceptor composite for efficient photoinduced electron transfer and light energy conversion”,
Chem. Commun., 3372-3374 (2008). (DOI: 10.1039/B806748A)

149. D’Souza, Francis; Rogers, Lisa M.; Islam, D.-M. Shafiqul; Araki, Yasuyuki; Ito, Osamu; Wada, Takehiko,
“Fluorescence resonance energy transfer between cationic porphyrins accelerated with DNA as a template”,
Chem. Lett., 37, 460-461 (2008). (DOI: 10.1246/cl.2008.460)

148. Pirrung, Michael C.; Bleecker, Anthony B.; Inoue, Yoshihisa; Rodriguez, Fernando I.; Sugawara, Norimitsu; Wada, Takehiko; Zou, Yunfan; Binder, Brad M,
“Ethylene receptor antagonists: strained alkenes are necessary but not sufficient”,
Chem. Biol. (Oxford, U. K.), 15, 313-321 (2008). (DOI: 10.1016/j.chembiol.2008.02.018)

147. Saito, Hideaki; Mori, Tadashi; Origane, Yumi; Wada, Takehiko; Inoue, Yoshihisa,
“Chiroptical properties and racemization behavior of highly distorted donor-acceptor tetracyanoanthraquinodimethane with interconvertible planar chirality”,
Chirality, 20, 278-281 (2008). (DOI: 10.1002/chir.20427)

146. Lu, Runhua; Yang, Cheng; Cao, Yujuan; Wang, Zhizhong; Wada, Takehiko; Jiao, Wei; Mori, Tadashi; Inoue, Yoshihisa,
“Supramolecular enantiodifferentiating photoisomerization of cyclooctene with modified beta-cyclodextrins: critical control by a host structure”,
Chem. Commun., 374-376 (2008). (DOI: 10.1039/B714300A)

2007年

145．Nishijima, Masaki; Wada, Takehiko; Mori, Tadashi; Pace, Tamara C. S.; Bohne, Cornelia; Inoue, Yoshihisa,
“Highly Enantiomeric Supramolecular [4 + 4] Photocyclodimerization of 2-Anthracenecarboxylate Mediated by Human Serum Albumin”,
J Am. Chem. Soc., 129, 3478-3479 (2007). (DOI: 10.1021/ja068475z)

144．Nishijima, Masaki; Pace, Tamara C. S.; Nakamura, Asao; Mori, Tadashi; Wada, Takehiko; Bohne, Cornelia; Inoue, Yoshihisa,
“Supramolecular Photochirogenesis with Biomolecules. Mechanistic Studies on the Enantiodifferentiation for the Photocyclodimerization of 2-Anthracenecarboxylate Mediated by Bovine Serum Albumin”,
J. Org. Chem., 72, 2707-2715 (2007). (Cover picture, The April Calendar of JOC in 2008) (DOI: 10.1021/jo062226b)

143．Nishiyama, Yasuhiro; Kaneda, Masayuki; Asaoka, Sadayuki; Saito, Ryota; Mori, Tadashi; Wada, Takehiko; Inoue, Yoshihisa,
“Mechanistic Study on the Enantiodifferentiating Anti-Markovnikov Photoaddition of Alcohols to 1,1-Diphenyl-1-alkenes in Near-Critical and Supercritical Carbon Dioxide”,
J. Phys. Chem. A, 111, 13432-13440 (2007). (DOI: 10.1021/jp076179i)

142．Yang, Cheng; Ko, Young Ho; Selvapalam, Narayanan; Origane, Yumi; Mori, Tadashi; Wada, Takehiko; Kim, Kimoon; Inoue, Yoshihisa,
“Dynamic Switching between Single- and Double-Axial Rotaxanes Manipulated by Charge and Bulkiness of Axle Termini”,
Org. Lett., 9, 4789-4792 (2007). (DOI: 10.1021/ol702142j)

141．Fukuhara, Gaku; Madenci, Suereyya; Polkowska, Jolanta; Bastkowski, Frank; Klaerner, Frank-Gerrit; Origane, Yumi; Kaneda, Masayuki; Mori, Tadashi; Wada, Takehiko; Inoue, Yoshihisa,
“Inherently chiral molecular clips: synthesis, chiroptical properties, and application to chiral discrimination”,
Chem. – Eur. J., 13, 2473-2479 (2007). (Cover picture) (DOI: 10.1002/chem.200601585)

140．Yang, Cheng; Mori, Tadashi; Wada, Takehiko; Inoue, Yoshihisa,
“Supramolecular enantiodifferentiating photoisomerization of (Z,Z)-1,3-cyclooctadiene included and sensitized by naphthalene-modified cyclodextrins”,
New J. Chem., 31, 697-702 (2007). (DOI: 10.1039/B615353D)

139．Fleck, Martin; Yang, Cheng; Wada, Takehiko; Inoue, Yoshihisa,
“Bach, Thorsten., Regioselective [2 + 2]-photocycloaddition reactions of chiral tetronates-influence of temperature, pressure, and reaction medium”,
Chem. Commun., 822-824 (2007). (DOI: 10.1039/B613985J)

138．Yang, Cheng; Nishijima, Masaki; Nakamura, Asao; Mori, Tadashi; Wada, Takehiko; Inoue, Yoshihisa,
“A remarkable stereoselectivity switching upon solid-state versus solution-phase enantiodifferentiating photocyclodimerization of 2-anthracenecarboxylic acid mediated by native and 3,6-anhydro-γ -cyclodextrins”,
Tetrahedron Lett., 48, 4357-4360 (2007). (DOI: 10.1016/j.tetlet.2007.04.104)

137．Yang, Cheng; Fukuhara, Gaku; Nakamura, Asao; Origane, Yumi; Mori, Tadashi; Wada, Takehiko; Inoue, Yoshihisa,
“Enhanced ternary 1:2 host-guest complexation of amino-γ -cyclodextrins with 2-anthracenecarboxylic acid”,
J. Inclusion Phenom. Macrocyclic Chem., 57, 433-437 (2007). (DOI: 10.1007/s10847-006-9230-y)

136．Fukuhara Gaku; Madenci Sureyya; Polkowska Jolanta; Bastkowski Frank; Klarner Frank-Gerrit; Origane Yumi; Kaneda Masayuki; Mori Tadashi; Wada Takehiko; Inoue Yoshihisa,
“Inherently chiral molecular clips: synthesis, chiroptical properties, and application to chiral discrimination”,
Chem. – Eur. J., 13, 2473-2479 (2007). (DOI: 10.1002/chem.200601585)

135．Nishiyama, Yasuhiro; Wada, Takehiko; Mori, Tadashi; Inoue, Yoshihisa,
“Critical control by temperature and pressure of enantiodifferentiating anti-markovnikov photoaddition of methanol to diphenylpropene in near critical and supercritical carbon dioxide”,
Chem. Lett., 36, 1488-1489 (2007). (DOI: 10.1246/cl.2007.1488)

134．Sakeda, Kosaku; Wakabayashi, Kazuhito; Matsushita, Yoshihisa; Ichimura, Teijiro; Suzuki, Tadashi; Wada, Takehiko; Inoue, Yoshihisa,
“Asymmetric photosensitized addition of methanol to (R)-(+)-(Z)-limonene in a microreactor”,
J. Photochem. Photobiol., A, 192, 166-171 (2007). (DOI: 10.1016/j.jphotochem.2007.05.019)

2006年

133. T. Wada, Y. Maeda, N. Sawa, H. Sato, H. Chon, S. Kanaya, Y. Inoue,
“Synthesis of peptide ribonucleic acids (PRNA) – DNA chimera and control of RNase H activity by external factor”,
Peptide Science 222 (2006).

132. G. Fukuhara, T. Mori, T. Wada, and Y. Inoue,
“Entropy-Controlled Supramolecular Photochirogenesis: Enantiodifferentiating Z-E Photoisomerization of Cyclooctene Included and Sensitized by Permethylated 6-O-Modified β-Cyclodextrins”,
J. Org. Chem., 71, 8233-8243 (2006). (DOI: 10.1021/jo061389x)

131. J. Mizoguchi, Y. Kawanami, T. Wada, K. Kodama, K. Anzai, T. Yanagi, and Y. Inoue,
“Enantiodifferentiating Photocyclodimerization of 2-Anthracenecarboxylic Acid Using a Chiral N-(2-Hydroxymethyl-4-pyrrolidinyl)benzamide Template”,
Org. Lett., 8, 6051-6054 (2006). (DOI: 10.1021/ol062501g)

130. T. Wada, Y. Maeda, N. Sawa, H. Sato, S. Futaki, and Y. Inoue,
“RNA Recognition and Recognition Control of α-Peptide Ribonucleic Acids Containing Arginine Residue by External Factors”,
Nucleic Acids Symp. Ser., 50, 75-76 (2006). (DPI: 10.1093/nass/nrl037)

129. J. Mizoguchi, T. Wada, and Y. Inoue,
“Solvent switching of stereoselectivity in [4 + 4] photocyclodimerization of 2-anthracenecarboxylic acid”,
Chem. Lett. 35, 738-739 (2006). (DOI: 10.1246/cl.2006.738)

128. C. Yang, A. Nakamura, T. Wada, and Y. Inoue,
“Enantio-Differentiating Photo-Cyclodimerization of 2-Anthracene-Carboxylic Acid Mediated by β‐Cyclodextrins with a Flexible or Rigid Cap”,
Org. Lett., 8, 3005-3008 (2006). (DOI: 10.1021/ol061004x)

127. G. Fukuhara, T. Mori, T. Wada, and Y. Inoue,
“The first supramolecular photosensitization of enantiodifferentiating bimolecular reaction: anti-Markovnikov photoaddition of methanol to 1,1-diphenylpropene sensitized by modified β-cyclodextrin”,
Chem. Commun., 1712-1714 (2006). (DOI: 10.1039/B601674J )

126. H. Saito, T. Mori, T. Wada, and Y. Inoue,
“Switching of Product’s Chirality in Diastereodifferentiating [2+2] Photocycloaddition of (E)- versus (Z)-Stilbene to Chiral Fumarate upon Direct and Charge-Transfer-Band Excitation”,
Org. Lett., 8, 1909-1912 (2006). (DOI: 10.1021/ol060468s)

125. C. Yang, A. Nakamura, G. Fukuhara, Y. Origane, T. Mori, T. Wada, and Y. Inoue,
“Pressure and Temperature-Controlled Enantio-Differentiating [4+4]-Photo-Cyclodimerization of 2-Anthracene-carboxylate Mediated by Secondary Face- and Skeleton-Modified β‐Cyclodextrins”,
J. Org. Chem., 71, 3126-3136 (2006). (DOI: 10.1021/jo0601718)

124. T. Furo, T. Mori, Y. Origane, T. Wada, H. Izumi, and Y. Inoue,
“Absolute configuration determination of donor-acceptor [2.2]paracyclophanes by comparison of theoretical and experimental vibrational circular dichroism spectra”,
Chirality, 18, 205-211 (2006). (DOI: 10.1002/chir.20233)

123. C. Schiel, G. A. Hembury, V. V. Borovkov, M. Klaes, C. Agena, T. Wada, S. Grimme, Y. Inoue, and J. Mattay,
“New Insights into the Geometry of Resorc[4]arenes: Solvent-Mediated Supramolecular Conformational and Chiroptical Control”,
J. Org. Chem. 71, 976-982 (2006). (DOI: 10.1021/jo0518654)

2005年

122. T. Furo, T.Mori, T.Wada, and Y.Inoue,
“Absolute Configuration of Chiral [2.2]Paracyclophanes with Intramolecular Charge-Transfer Interaction. Failure of the Exciton Chirality Method and Use of the Sector Rule Applied to the Cotton Effect of the CT Transition”,
J. Am. Chem. Soc., 127, 8242-8243 (2005). (DOI: 10.1021/ja0508323)

121. G.Fukuhara, T.Mori, T. Wada, and Y.Inoue,
“Entropy-controlled supramolecular photochirogenesis: enantiodifferentiating Z-E photoisomerization of cyclooctene included and sensitized by permethylated 6-O-benzoyl- β-cyclodextrin”,
Chem. Commun., 4199-4201 (2005). (DOI: 10.1039/B504948B)

120. T. Wada and Y. Inoue,
“Peptide ribonucleic acids (PRNA): novel strategy for active control of DNA recognition by external factors”,
Proteins, Nucleic Acid, Enzyme, 50, 463-470 (2005).

119. Y.Gao, T. Wada, K.Yang, K. Kim, and Y.Inoue,
“Supramolecular photochirogenesis in sensitizing chiral nanopore: Enantiodifferentiating photoisomerization of (Z)-cyclooctene included and sensitized by POST-1″,
Chirality, 17, S19-S23 (2005). (DOI: 10.1002/chir.20102)

118. Enantiodifferentiating [4+4] photocyclodimerization of 2-anthracenecarboxylate catalyzed by 6A,6X-diamino-6A,6X-dideoxy-γ-cyclodextrins: Manipulation of product chirality by electrostatic interaction, temperature and solvent in supramolecular photochirogenesis.
C.Yang, G.Fukuhara, A.Nakamura, Y.Origane, K.Fujita, T.Wada, and Y.Inoue,
J. Photochem. Photobiol., A, 173, 375-383 (2005). (DOI: 10.1016/j.jphotochem.2005.04.017)

117. Y.Liu, H.Wang, R.Cao,T.Wada, and Y. Inoue,
“Diastereomeric Molecular Recognition and Binding Behavior of Bile Acids by L/D-Tryptophan-Modified γ-Cyclodextrins”,
J. Org. Chem., 70, 8703-8711 (2005). (DOI: 10.1021/jo051073+)

116. J.Sivaguru, T.Wada, Y.Inoue, and V.Ramamurthy, V.,
“Mechanism of photoisomerization of optically pure trans-2,3-diphenylcyclopropane-1-carboxylic acid derivatives”,
Photochem. Photobiol. Sci., 4, 119-127 (2005). (DOI: 10.1039/B410480C)

115. T. Wada and Y. Inoue,
“Functionalization of PNA – novel strategy for active control of DNA recognition by external factors using peptide ribonucleic acids (PRNA)”,
Yuki Gosei Kagaku Kyokaishi 63, 63 (2005).

2004年

114. T. Wada, Y. Hashimoto, H. Sato, and Y. Inoue,
“Synthesis of Peptide Ribonucleic Acid Consisting of D- and L-γ-Glutamic Acid as a Backbone Structure”,
Nucleic Acids Symp. Ser., 48, 27-28 (2004). (DOI: 10.1093/nass/48.1.27)

113. H. Saito, T. Mori, T. Wada, and Y. Inoue,
“Diastereoselective [2 + 2] Photocycloaddition of Stilbene to Chiral Fumarate. Direct versus Charge-Transfer Excitation”,
J. Am. Chem. Soc., 126, 1900-1906 (2004). (DOI: 10.1021/ja0370140)

112. Y. Nishiyama, M. Kaneda, R. Saito, T. Mori, T. Wada, and Y. Inoue,
“Enantiodifferentiating Photoaddition of Alcohols to 1,1-Diphenylpropene in Supercritical Carbon Dioxide: Sudden Jump of Optical Yield at the Critical Density”,
J. Am. Chem. Soc., 126, 6568-6569 (2004). (DOI: 10.1021/ja0494609)

111. T.Wada, H. Sato and Y. Inoue,
“External Reversible Control of Recognition Behavior of Alpha-Peptide Ribonucleic acid (α-PRNA) through Anti-Syn Orientational Switching of the Nucleobase Induced by Borate Esterification of the cis-2′,3′-Diol”,
Pept. Sci., 76, 15-20 (2004). (DOI: 10.1002/bip.10563)

110. T. Wada Y. Inoue,
“Active control of DNA recognition behavior of α-peptide ribonucleic acids containing basic amino acid residues by external factors”,
Polym. Prepr. (Am. Chem. Soc., Div. Polym. Chem.), 45, 447 (2004).

109. M. Kaneda, Y. Nishiyama, S. Asaoka, T. Mori, T. Wada, and Y. Inoue,
“Pressure control of enantiodifferentiating polar addition of 1,1-diphenylpropene sensitized by chiral Naphthalenecarboxylates”,
Org. Biomol. Chem., 2, 1295-1303 (2004). (DOI: 10.1039/B401108B)

108. Y. Liu, Y. Yang, Y. Song, H. Zhang, T. Wada, and Y. Inoue,
“Residue- and sequence-selective binding of nonaromatic dipeptides by bis(β-cyclodextrin) with a functional tether”,
ChemBioChem., 5, 868-871 (2004). (10.1002/cbic.200300770)

107. J. Sivaguru, B. Raghavan. T. Wada, Y. Origane, Y. Inoue, and V. Ramamurthy,
“Enhanced Diastereoselectivity via Confinement: Diastereoselective Photoisomerization of 2,3-Diphenyl-1-benzoylcyclopropane Derivatives within Zeolites”,
J. Org. Chem., 69, 5528-5536 (2004). (DOI: 10.1021/jo049697n)

106. J. Sivaguru, B. Raghavan. T. Wada, Y. Origane, Y. Inoue, and V. Ramamurthy,
“Enhanced Diastereoselectivity via Confinement: Photoisomerization of 2,3-Diphenylcyclopropane-1-carboxylic Acid Derivatives within Zeolites”,
J. Org. Chem., 69, 6533-6547 (2004). (DOI: 10.1021/jo049365i)

105. B. Grosch, C. Orlebar, M. Kaneda, T. Wada, Y. Inoue, and T. Bach,
“Enantioselective [4+2]-cycloaddition reaction of a photochemically generated o-Quinodimethane: Mechanistic details, association studies, and pressure effects”,
Chem. -Eur. J., 10, 2179-2189 (2004). (DOI: 10.1002/chem.200306049)

104. H. Sato, T. Wada, and Y. Inoue,
“Synthesis and Conformation Control of Peptide Ribonucleic Acid (PRNA) Containing 5′-Amino-5′-deoxyribopyrimidine and 5′-Amino-5′-deoxyribopurinenucleosides”,
J. Bioact. Compat. Polym., 19, 65-79 (2004). (DOI: 10.1177/0883911504042640)

103. H. Saito, T. Mori, T. Wada, and Y. Inoue,
“Pressure control of diastereodifferentiating [2 + 2] photocycloaddition of (E)-stilbene to chiral fumarate upon direct and charge-transfer excitation”,
Chem. Comm., 1652-1653 (2004). (DOI: 10.1039/B404555F)

102. T. Mori, M. Takamoto, H. Saito, T. Furo, T. Wada, and Y. Inoue,
“Remarkable differences in photo and thermal (acid-catalyzed) reactivities between ortho- and para-acylcyclohexadienones as essential factors determining the overall efficiency of the photo-Fries rearrangement”,
Chem. Lett., 33, 256-257 (2004). (DOI: 10.1246/cl.2004.256)

101. Mori, Tadashi; Takamoto, Makoto; Saito, Hideaki; Furo, Takahiro; Wada, Takehiko; Inoue, Yoshihisa,
“Isolation of cyclohexadienone intermediates in the photo-Fries rearrangement of 2,4-dimethylnaphth-1-yl and 1,4-dimethylnaphth-2-yl 2,4,6-trimethylbenzoates”,
Chem. Lett., 33, 254 (2004). (DOI: 10.1246/cl.2004.254)

2003年

100. Wada, Takehiko; Nishijima, Masaki; Fujisawa, Tai; Sugahara, Norimitsu; Mori, Tadashi; Nakamura, Asao; Inoue, Yoshihisa,
“Bovine Serum Albumin-Mediated Enantiodifferentiating Photocyclodimerization of 2-Anthracenecarboxylate”,
J. Am. Chem. Soc. 125, 7492-7493 (2003). (DOI: 10.1021/ja034641g)

99. Wada, Takehiko; Sato, Hirofumi; Hashimoto, Yusuke; Inoue, Yoshihisa,
“Solid-Phase Synthesis of Peptide Ribonucleic Acids (PRNA)”,
Tetrahedron, 59, 7871-7878 (2003). (DOI: 10.1016/j.tet.2003.08.024)

98. Liu, Yu; Fan, Zhi; Zhang, Heng -Y; Yang, Ying -W; Ding, Fei; Liu, Shuang -X; Wu, Xue; Wada, Takehiko; Inoue, Yoshihisa,
“Supra-Molecular Self-Assemblies of β-Cyclodextrins with Aromatic Tethers: Factors Governing the Helical Columnar versus Linear Channel Super-Structures”,
J. Org. Chem. 68, 8345-8352 (2003). (DOI: 10.1021/jo034632q)

97. Wada, Takehiko; Sato, Hirofumi; Inoue, Yoshihisa;
“A Novel Strategy for Reversible Control of Conformation and DNA/RNA Recognition of Peptide Ribonucleic Acid (PRNA) by External Factors”,
Nucleic Acids Symp. Ser., 3, 213-214 (2003). (DOI: 10.1093/nass/3.1.213)

96. Kaneda, Masayuki; Nakamura, Asao; Asaoka, Sadayuki; Ikeda, Haruhiko; Wada, Takehiko; Inoue, Yoshihisa,
“Pressure control of enantiodifferentiating photoisomerization of cyclooctenes sensitized by chiral benzenepolycarboxylates. The origin of discontinuous pressure dependence of the optical yield”,
Org. Biomol. Chem., 1, 4435-4440 (2003). (DOI: 10.1039/B310491E)

95. Mori, Tadashi; Takemoto, Makoto; Wada, Takehiko; Inoue, Yoshihisa,
“Acid-controlled photoreactions of aryl alkanoates: competition of trans-esterification, decarboxylation, Fries-rearrangement and/or transposition”,
Photochem. Photobiol. Sci, 2, 1187-1199 (2003). (DOI: 10.1039/B305898K)

94. Liu, Yu; Song, Yun; Wang, Hao; Zhang, Heng -Y; Wada, Takehiko; Inoue, Yoshihisa,
“Selective Binding of Steroids by 2,2′-Biquinoline-4,4′-dicarboxamide-Bridged Bis(β-cyclodextrin): Fluorescence Enhancement by Guest Inclusion”,
J. Org. Chem. 68, 3687-3690 (2003). (DOI: 10.1021/jo026908k)

93. Hasegawa, Yasuchika; Tomita, Taiji; Wada, Yuji; Wada, Takehiko; Inoue, Yoshihisa; Yanagida, Shozo,
“Detail CD spectra analysis in view of angular momentum using chiral Eu(III) complexes”,
Kidorui, 42, 132-133 (2003).

92. Liu, Yu; Li, Li; Li, Xiao -Y; Zhang, Heng -Y; Wada, Takehiko; Inoue, Yoshihisa,
“Synthesis of Phosphoryl-Tethered β-Cyclodextrins and Their Molecular and Chiral Recognition Thermodynamics”,
J. Org. Chem., 68, 3646-3657 (2003). (DOI: 10.1021/jo026852u)

91. Klaes, Michael; Agena, Ceno; Köhler, Markus; Inoue, Maki; Wada, Takehiko; Inoue, Yoshihisa; Mattay, Jochen,
“First synthesis, isolation and characterization of enantiomerically pure and inherently chiral resorc[4]arenes by lewis acid cyclization of a resorcinol monoalkyl ether”,
Eur. J. Org. Chem., 1404-1409 (2003). (DOI: 10.1002/ejoc.200390197)

90. Asaoka, Sadayuki; Wada, Takehiko; Inoue, Yoshihisa,
“Microenvironmental Polarity Control of Electron-Transfer Photochirogenesis. Enantiodifferentiating Polar Addition of 1,1-Diphenyl-1-alkenes Photosensitized by Saccharide Naphthalenecarboxylates”,
J. Am. Chem. Soc., 125, 3008-3027 (2003). (DOI: 10.1021/ja028680o)

解説・総説

19.　独自のアイデア・仮説を自分で合成した分子を用いて実証する醍醐味，和田健彦，化学，64，24 (2009).
18.　高分子学会会誌「高分子」11月号 “Hot Topics” , 和田健彦，2008年11月.
17.　刺激応答性人工核酸を用いたナノバイオ分子の開発, 和田健彦, Antisense, 12, 36-41(2008).
16.　外部刺激応答性人工核酸の創製　−がん細胞特異的遺伝子治療薬の開発を目指して−, 和田健彦, 日本化学会バイオテクノロジー部会ニュースレター, 12, 4-6 (2008).　
15.　ケミカルバイオロジーに新パラダイムを提案したい！，和田健彦，化学，62，13 (2007).
14.　化学の力で遺伝情報をコントロールする人工核酸，和田健彦，日刊工業新聞，2005年11月1日朝刊.
13.　外部刺激応答性機能核酸の創製，和田健彦,井上佳久, PNE(タンパク質・核酸・酵素)50, 463(2005).
12.　ペプチド核酸の新展開‐刺激応答性核酸の構築‐,和田健彦,井上佳久, 有機合成化学協会誌 63, 63 (2005).
11.　刺激応答性人工核酸の創製，和田健彦，生物工学会誌, 82, 142(2004).
10.　ペプチド核酸の新展開‐外部因子による核酸認識制御機能を有する核酸モデル（PRNA）の設計・合成・機能‐，和田健彦，バイオマテリアル，21, 278 (2003).
9.　-遺伝子機能を人工的に利用する-機能性材料としての人工遺伝子，和田健彦，日刊工業新聞，2002年10月1日朝刊.
8.　遺伝情報の自在な機能発現制御を目指して‐外部因子による核酸認識制御機能を有する核酸モデル（PRNA）の設計・合成・機能‐，和田健彦，物性研究，79, 410 (2002).
7.　遺伝情報の外部因子による制御を目指した核酸モデルの構築，和田健彦，化学工業，53，443 (2002).
6.　Asymmetric Photoreaction under High Pressure -Pressure Control of Product Chirality-,
M. Kaneda, T. Wada, and Y. Inoue,
The Review of High Pressure Science and Technology, 11, 227 (2001).
5.　Studies on enantiodifferentiating photosensitization using DNA as chiral sensitizer and/or reaction field
T. Wada, Y. Inoue,
Asahi Garasu Zaidan Josei Kenkyu Seika Hokoku (1999).
4.　核酸研究における光化学反応の活用, 和田健彦, 井上佳久, 化学, 53, 68-69 (1998).
3.　核酸を用いた高効率光増感機能の発現, 和田健彦, 井上佳久, 生産と技術, 49, 56 (1997).
2.　光化学を用いたDNA研究の新展開, 和田健彦、井上佳久, 光化学, 23, 56 (1996).
1.　夢の人工核酸へのアプローチ – 人工核酸は核酸を超えられるか -, 和田健彦,高分子,42,933(1993).

著　　書

9.　Functional Artificial Nucleic Acids: Peptide Ribonucleic Acids (PRNAs) – Novel Strategy for Active Control of DNA Recognition by External Factors-ﾒ T. Wada, Advances in Organic Chemistry – Online, A. Rahman and Y. Hayakawa Ed; Bentham Science PublisherLtd., USA 243 (2005).
8.　Supramolecular Asymmetric Photoreactions, T. Wada and Y. Inoue,
Organic Molecular Photochemistry; Ramamurthy, V.; Inoue, Y. Ed.; Marcel Dekker: New York, 341 (2004).
7．「高分子辞典（第3版）」，和田健彦分担執筆, 高分子学会編,朝倉書店，2005年6月.
6.　「一目で分かる先端科学の基礎」，和田健彦分担執筆, 野村正勝、小松満男、町田憲一編,大阪大学出版会，2002年7月.
5.　｢生命化学のﾆｭｰｾﾝﾄﾗﾙﾄﾞｸﾞﾏ｣，和田健彦分担執筆, 杉本直己編, 化学同人(株)，2002年2月.
4.　「生命高分子化学入門」, 和田健彦共著, 講談社サイエンティフィック, 1999年4月．
3.　分子認識のしくみ 「分子認識化学」，井上佳久, 和田健彦分担執筆，築部浩編, 三共出版, 1997年2月．
2.　Nucleic Acid Analogs (Syntheses and Properties),
T. Wada, Y. Inaki, and K. Takemoto,
The Polymeric Materials Encyclopedia: Synthesis, Properties and Applications,
J. C. Salamone and M. Lowell Eds., CRC Press Inc., Boca Raton, FL, USA, 94-108 (1996).
1.　「人工核酸」-合成・機能・応用-, 稲木良昭編著、和田健彦、望月衛子著、IPC出版、1992 年 11 月．

特　　許

・ 極低温紫外可視、蛍光ならびに円二色性スペクトル測定用セルホルダー：井上佳久、和田健彦、岡本基土、中川達央

 

特許出願番号：平成21年9月7882006JP

 

・アンチセンス分子及びそれを用いた遺伝子機能発現の制御方法：和田健彦、井上佳久

 

特許番号JP2001-096356　出願年月日　平成13年6月13日

 

PTC国際特許出願　平成14年6月　現在審査中

 

・ヌクレオシド誘導体：井上佳久、和田健彦

 

特許番号JP2001-096355　出願年月日　平成13年6月13日

 

PTC国際特許出願　平成14年6月　現在審査中

 

・チミンを用いた光記録材料：竹本喜一、稲木良昭、和田健彦

 

特許番号 JP 1992-354813　出願年月日　平成4年12月18日