![\"\"](\"http:\/\/www.tagen.tohoku.ac.jp\/uploads\/fckeditor\/user\/image\/www90\/sozai\/pen_01.gif\")
<\/p>\n<\/p>\n
\u00a0No.37\u30002012.3.23 \u62c5\u5f53\u8005\uff1a\u6e21\u8fba\u512a \u8ad6\u6587\uff1aProtein-binding dynamics imaged in…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":151,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-168","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www2.tagen.tohoku.ac.jp\/lab\/takahashi-s\/wp-json\/wp\/v2\/pages\/168","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www2.tagen.tohoku.ac.jp\/lab\/takahashi-s\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www2.tagen.tohoku.ac.jp\/lab\/takahashi-s\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www2.tagen.tohoku.ac.jp\/lab\/takahashi-s\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www2.tagen.tohoku.ac.jp\/lab\/takahashi-s\/wp-json\/wp\/v2\/comments?post=168"}],"version-history":[{"count":1,"href":"https:\/\/www2.tagen.tohoku.ac.jp\/lab\/takahashi-s\/wp-json\/wp\/v2\/pages\/168\/revisions"}],"predecessor-version":[{"id":169,"href":"https:\/\/www2.tagen.tohoku.ac.jp\/lab\/takahashi-s\/wp-json\/wp\/v2\/pages\/168\/revisions\/169"}],"up":[{"embeddable":true,"href":"https:\/\/www2.tagen.tohoku.ac.jp\/lab\/takahashi-s\/wp-json\/wp\/v2\/pages\/151"}],"wp:attachment":[{"href":"https:\/\/www2.tagen.tohoku.ac.jp\/lab\/takahashi-s\/wp-json\/wp\/v2\/media?parent=168"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}![\"\"](\"http:\/\/www.tagen.tohoku.ac.jp\/uploads\/fckeditor\/user\/image\/www90\/sozai\/pen.gif\")
\u00a0No.37\u30002012.3.23
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u6e21\u8fba\u512a
\n\u8ad6\u6587<\/strong>\uff1aProtein-binding dynamics imaged in a living cell
\nYael Philip et
\nPNAS<\/em>\/ January 31,2012\/ vol.109<\/strong>\/ no.5\/ 1461-1466<\/p>\n\u00a0No.36\u30002012.3.16
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u9ad8\u6a4b\u8056\u5f25
\n\u8ad6\u6587<\/strong>\uff1aInfluence of drying on the secondary structure of intrinsically disordered and globular proteins
\nMichaela Hundertmark et al.
\nBiochemical and Biophysical Research Communications<\/i> <\/i>417<\/strong>(2012) 122-128<\/p>\n\u00a0No.35\u30002012.2.24
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u4e2d\u91ce\u99ff\u4ecb
\n\u8ad6\u6587<\/strong>\uff1aSingle-vesicle estimation of ATP-binding cassete transporters in microfluidic channels
\nHiroataka Sasaki et al.
\nLob Chip<\/em>,2012,12<\/strong>,702-704<\/p>\n\u00a0No.34\u30002012.2.17
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u5c0f\u4e95\u5ddd\u6d69\u4e4b
\n\u8ad6\u6587<\/strong>\uff1aExploring one-state downhill protein folding in single molecules
\nJianwei Liu et al.
\nPNAS<\/em>, vol.109, 179-184 \uff082012\uff09<\/p>\n\u00a0No.33\u30002012.2.10
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u938c\u5f62\u6e05\u4eba
\n\u8ad6\u6587<\/strong>\uff1aProbing Single-Molecule Enzyme Active-Site Conformational State Intermittent Coherence
\nYufan He et al.
\nJ.Am.Chem.Soc<\/em>. 2011, 133<\/strong>,14389-14395<\/p>\n\u00a0No.32\u30002012.2.3
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u6e21\u8fba\u512a
\n\u8ad6\u6587<\/strong>\uff1aDomain-Specific Folding Kinetics of Staphylococcal Nuclease Observed through Single-Molecule FRET in a Microfluidic Mixer
\nZeyong Zhi et al.
\nChemPhysChem<\/em> (2011)<\/p>\n\u00a0No.31\u30002012.1.27
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u9ad8\u6a4b\u8061
\n\u8ad6\u6587<\/strong>\uff1aSingle-Molecule Lysozyme Dynamics Monitored by an Electronic Circuit
\nYongki Choi et al.
\nScience<\/em> vol.335<\/strong> 20 January 2012 (319- )<\/p>\n\u00a0No.30\u30002012.1.20
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u9ad8\u6a4b\u8056\u5f25
\n\u8ad6\u6587<\/strong>\uff1aVisualization of Intrinsically Disordered Regions of Proteins by High-Speed Atomic Force Microscopy
\nAtsushi Miyagi et al.
\nChemphysChem<\/em> 2008, 9<\/strong>, 1859-1866<\/p>\n\u00a0No.29\u30002012.1.13
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u658e\u85e4\u7fd4
\n\u8ad6\u6587<\/strong>\uff1aHighly Parallel Single-Molecule Amplification Approach Based on Agarose Droplet Polymerase Chain Reaction for Efficient and Cost-Effective Aptamer Selection
\nWei Yun Zhang et al.
\nAnal. Chem.<\/em> 2012,84<\/strong>,350-355<\/p>\n\u00a0No.28\u30002011.12.16
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u9234\u6728\u96c4\u592a
\n\u8ad6\u6587<\/strong>\uff1aSingle-Molecule FRET Ruler Based on Rigid DNA Origami Blocks
\nIngo H.Stein et al.
\nChemPhysChem<\/em> 2011,12<\/strong>,689-695<\/p>\n\u00a0No.27\u30002011.12.9
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u4e2d\u91ce\u99ff\u4ecb
\n\u8ad6\u6587<\/strong>\uff1aOpening the periplasmic cavity in lactose permease is the limiting step for sugar binding
\nIrina Sminova et al.
\nPNAS<\/em>, vol.108<\/strong>, 2011, 15147-15151<\/p>\n\u00a0No.26\u30002011.12.2
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u5c0f\u4e95\u5ddd\u6d69\u4e4b
\n\u8ad6\u6587<\/strong>\uff1aThe Fast and the Slow: Folding and Trapping of \u03bb6-85
\nMaxim B. Prigozhin and Martin Gruebele
\nJ.Am.Chem.Soc<\/em>. 2011,133<\/strong>(48),pp 19338-19341<\/p>\n\u00a0No.25\u30002011.11.25
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u938c\u5f62\u6e05\u4eba
\n\u8ad6\u6587<\/strong>\uff1aSingle-molecule fluorescence spectroscopy maps the folding landscape of a large protein
\nMenahem Pirchi et al.
\nNat Bommun<\/em>. 2011 Oct 11; 2: 493<\/p>\n\u00a0No.24\u30002011.11.18
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u9ad8\u6a4b\u8061
\n\u8ad6\u6587<\/strong>\uff1aHow Fast-Folding Proteins Fold
\nKresten Lindorff-Larsen et al.
\nSCIENCE<\/em> vol.334<\/strong> 28 October 2011<\/p>\n\u00a0No.23\u30002011.11.11
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u6e21\u8fba\u512a
\n\u8ad6\u6587<\/strong>\uff1aAnalysis of peptides and proteins in their binding to GroEL
\nYali Li et al.
\nJ. pept. Sci<\/em>.2010; 16<\/strong>:693-700<\/p>\n\u00a0No.22\u30002011.11.4
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u9234\u6728\u96c4\u592a
\n\u8ad6\u6587<\/strong>\uff1aMulticolor single-molecule FRET to explore protein folding and binding
\nYann Gambin and Ashok A. Deniz
\nMol.BioSyst<\/em>., 2010, 6<\/strong>, 1540-1547<\/p>\n\u00a0No.21\u30002011.10.28
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u6589\u85e4\u7fd4
\n\u8ad6\u6587<\/strong>\uff1aMicrofluidic active sorting of DNA molecules labeled with single quantum dots using flow switching by a hydrogel sol-gel transition
\nMai Haneoka et al.
\nAensors and Actuators B<\/em> 159 (2011) 314-320<\/p>\n\u00a0No.20\u30002011.10.21
\n\u62c5\u5f53\u8005<\/strong>\uff1a\ufffd\u6a4b\u8056\u5f25
\n\u8ad6\u6587<\/strong>\uff1aA combined atomic force microscopy imaging and docking study to investigate the complex between p53 DNA binding domain and Azurin
\nAnna Rita Bizzarri et al.
\nJ Mol Recognit.<\/em> (2009) Nov-Dec;22(6):506-515<\/p>\n\u00a0No.19\u30002011.10.14
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u5ddd\u53e3\u654f\u53f2
\n\u8ad6\u6587<\/strong>\uff1aA combined single-molecule FRET and tryptophan fluorescence study of RNase H folding under acidic conditions
\nRobert Rieger, G. Ulrich Nienhaus
\nChemical Physics<\/em> (2011)<\/p>\n\u00a0No.18\u30002011.10.7
\n\u62c5\u5f53\u8005<\/strong>\uff1a \u6e21\u8fba\u512a
\n\u8ad6\u6587<\/strong>\uff1aDenatured proteins facilitate the formation of the football-shaped GroEL-(GroES)2 complex
\nTomoya SAMESHIMA et al.
\nBiochem J <\/em>(2010) 427<\/strong>, 247-254<\/p>\n\u00a0No.17\u30002011.9.30
\n\u62c5\u5f53\u8005<\/strong>\uff1a \u677f\u6a4b\u88d5\u76f4
\n\u8ad6\u6587<\/strong>\uff1aSubstituent Effects of Protein Derivatives on Singlet Oxygen Scavenging Activity
\nHiroko Mori et al.
\nBiol. Pharm. Bull. 33(5) 2010, 905-908<\/p>\n\u00a0No.16\u30002011.9.9
\n\u62c5\u5f53\u8005<\/strong>\uff1a \u4e2d\u91ce\u99ff\u4ecb
\n\u8ad6\u6587<\/strong>\uff1aProbing of the rates of alternating access in LacY with Trp fluorescence
\nIrina Smirnovaa et al.
\nPNAS<\/em>,106, 2009,21561-21566<\/p>\n\u00a0No.15\u30002011.9.2
\n\u62c5\u5f53\u8005<\/strong>\uff1a \u5c0f\u4e95\u5ddd\u6d69\u4e4b
\n\u8ad6\u6587<\/strong>\uff1aSingle-molecule fluorescence reveals sequence-specific misfolding in multidomain proteins
\nMadeleine B. Borgia et al.
\nNature<\/em>, 474, 2011, 662-665<\/p>\n\u00a0No.14\u30002011.8.26
\n\u8ad6\u6587\u901f\u5831\u306e\u307f<\/p>\n\u00a0No.13\u30002011.8.19
\n\u62c5\u5f53\u8005<\/strong>\uff1a \u938c\u5f62\u6e05\u4eba
\n\u8ad6\u6587<\/strong>\uff1aTemperature-cycle single-molecule FRET microscopy on polyprolines
\nHaifeng Yuan et al.
\nPhys.Chem.Chem.Phys<\/em> 2011,13,1762-1769<\/p>\n\u00a0No.12\u30002011.8.5
\n\u62c5\u5f53\u8005<\/strong>\uff1a \ufffd\u6a4b\u8061
\n\u8ad6\u6587<\/strong>\uff1aProtein induced fluorescene enhancement as a single molecule assay with short distance sensitivity
\nHelen Hwang et al.
\nPNAS<\/em> (2011) 108, 7414-7418<\/p>\n\u00a0No.11\u30002011.7.29
\n\u62c5\u5f53\u8005<\/strong>\uff1a \u5b89\u85e4\u8a5e\u97f3
\n\u8ad6\u6587<\/strong>\uff1aSingle-molecule imaging by optical Absorption
\nMichele Celebrano et al.
\nNature Photonics<\/em> vol5, 2011<\/p>\n\u00a0No.10\u30002011.7.22
\n\u62c5\u5f53\u8005<\/strong>\uff1a \ufffd\u6a4b\u8056\u5f25
\n\u8ad6\u6587<\/strong>\uff1aRational drug design via intrinsically disordered protein
\nYugong Cheng et al.
\nTrends in Biotechnology,<\/em> vol.24, 10, 2006, 435-442<\/p>\n\u00a0No.9\u30002011.7.15
\n\u62c5\u5f53\u8005<\/strong>\uff1a \u9234\u6728\u96c4\u592a
\n\u8ad6\u6587<\/strong>\uff1aLong-Term Real-Time Tracking of Lanthanide Ion Doped Upconverting Nanoparticles in Living Cells
\nSang Hwan Nam et al.
\nAngew.Chem.Int Ed<\/em>. 2011,50<\/strong>,6093-6097<\/p>\n\u00a0No.8\u30002011.7.8
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u6589\u85e4\u7fd4
\n\u8ad6\u6587<\/strong>\uff1aHydrodynamic gating valve for microfluidic fluorescence-activated cell sorting
\nPu Chen et al.
\nAnalytica Chimica Acta<\/em> 663 (2010) 1-6<\/p>\n\u00a0No.7\u30002011.7.1
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u5ddd\u53e3\u654f\u53f2
\n\u8ad6\u6587<\/strong>\uff1aUnfolding dynamics of cytochrome c revealed by single-molecule and ensemble-averaged spectroscopy
\nJungkweon Choi et al.
\nPhys.Chem.Chem.Phys<\/em> (2011) ,13,5651-5658<\/p>\n\u00a0No.6\u30002011.6.16
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u677f\u6a4b\u88d5\u76f4
\n\u8ad6\u6587<\/strong>\uff1aQuenching of Singlet Oxygen by Pyocyanin and Related Phenazines
\nKrzysztof J. Reszka et al.
\nPhotochemistry and Photobiology<\/em>, 2010, 86: 742-746<\/p>\n\u00a0No.5\u30002011.6.10
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u5b89\u85e4\u8a5e\u97f3
\n\u8ad6\u6587<\/strong>\uff1aClpX(P) Generates Mechanical Force to Unfold and Translocate Its Protein Substrates
\nRodrigo A. Maillard et al.
\nCell<\/em> 145,459-469, April 29,2011<\/p>\n\u00a0No.4\u30002011.6.3
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u4e2d\u91ce\u99ff\u4ecb
\n\u8ad6\u6587<\/strong>\uff1aSubstrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue
\nYongfang Zhao et al.
\nNature letter <\/em>\uff082011\uff09<\/p>\n\u00a0No.3\u30002011.5.27
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u5c0f\u4e95\u5ddd\u6d69\u4e4b
\n\u8ad6\u6587<\/strong>\uff1aIdentifying Molecular Dynamics in Single-Molecule FRET Experiments with Burst Variance Analysis
\nJoseph P. Torella et al.
\nBiophysical Journal<\/em> Volume 100, 2011, Pages 1568-1577<\/p>\n\u00a0No.2\u30002011.5.20
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u938c\u5f62\u6e05\u4eba
\n\u8ad6\u6587<\/strong>\uff1aVisualizing a one-way protein enounter complex by ultrafast single-molecule mixing.
\nGambin Y et al.
\nNature Methods<\/em> 2011 Mar:8(3):239-41<\/p>\n\u00a0No.1\u30002011.5.13
\n\u62c5\u5f53\u8005<\/strong>\uff1a\u9ad8\u6a4b\u8061
\n\u8ad6\u6587<\/strong>\uff1aA photoprotection strategy for microsecond-resolution single-molecule fluorescence spectroscopy
\nLuis A Campos et al.
\nNature Methods <\/i>vol.8 No.2 \u00a0 (2011) 143<\/p>\n","protected":false},"excerpt":{"rendered":"