論文紹介2013

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 No.32 2014.3.17
担当者: 吉田文
論文:Evidence of an Intermediate and Parallel Pathways in Protein Unfolding from Single-Molecule Fluorescence
Angel Orte et al.
J. Am. Chem. Soc., 2008,130 (25), pp 7898-7907

 No.31 2014.3.10
担当者: 小井川浩之
論文:Continuous throughput and long-term observation of single-molecule FRET without immobilization
Swati Tyagi et al.
Nature Methods, vol.11, no.3, 2014

 No.30 2014.3.3
担当者: 鎌形清人
論文:Folding of tetrameric p53: oligomerization and tumorigenic mutations induce misfolding and loss of function.
Lubin DJ et al.
J. Mol. Biol. 2010 395(4) : 705-16

Kinetic partitioning during folding of the p53 DNA binding domain.
Butler JS et al.
J. Mol. Biol. 2005 350 (5) : 9906-18

 No.29 2014.2.24
担当者: 高橋聡
論文:Impact of reconstituted cytosol on protein stability
Mohona Sarkar et al.
PNAS (2013) 110, 19342-19347

 No.28 2014.2.17
担当者: 切口理恵
論文:Rapid protein-folding assay using green fluorescent protein
Geoffrey S. Waldo et al.
Nat Biotechnol. 1999 Jul;17(7):691-5.

 No.27 2014.2.10
担当者: 伊藤優志
論文:Ultrafast Hydrogen Exchange Reveals Specific Structural Events during the Initial Stages of Folding of Cytochrome
c
Hossein Fazelinia et al.
J. Am. Chem. Soc.,
2014, 136, 733-740

 No.26 2014.2.4
担当者: 阿蘇裕樹
論文:Two-Color, Laser Excitation Improves Temporal Resolution for Detecting the Dynamic, Plasmonic Coupling between MetallicNanoparticles
Diane M. Wiener and Troy A. Lionberger
Anal. Chem. 2013,85,5095-5102

 No.25 2014.1.27
担当者: 吉田文
論文:Folding of a large protein at high structural resolution
Benjamin T. Walters et al.
PNAS, vol. 110, no.47 (2013) 18898-18903

 No.24 2014.1.6
担当者: 鎌形清人
論文:Engineering of weak helper interactions fo high-efficiency FRET probes
Raik Grunberg et al.
Nature Methods Vol.10 No.10 1021-1027 (2013)

 No.23 2013.12.16
担当者: 小井川浩之
論文:Single-molecule fluorescence probes dynamics of barrier crossing
Hoi Sung Chung & William A. Eaton
Nature 502, 685-688 (2013)

 No.22 2013.11.25
担当者: 高橋聡
論文:Probing the protein-folding mechanism using denaturant and temperature effects on rate vonstants
Emily j. Guinn et al.
PNAS, vol.110, no.42, 16784-16789

 No.21 2013.11.18
担当者: 切口理恵
論文:Protein tagging and detection with engineered self-assembling fragments of green fluorescent protein
Cabantous, S. et al.
Nature biotechnology, 23(1), 102-107

 No.20 2013.11.11
担当者: 伊藤優志
論文:Folding and Binding of an Intrinsically Disordered Protein: Fast, but Not ‘Diffusion-Limited’
Joseph M. Rogers et al.
J.Am. Chem. Soc. 2013,135,1415-1422

 No.19 2013.10.21
担当者: 村田崇人
論文:Bypass of a protein barrier by a replicative DNA helicase
hasan Yardimci et al.
13. December, 2012, vol. 492, Nature

 No.18 2013.10.7
担当者: 齊藤雅嵩
論文:Polymer scaling laws of unfolded and intrinsically disordered proteins quantified with single-molecule spectroscopy
hagen Hofmann et al.
PNAS, vol.109, no.40, 16155-16160

 No.17 2013.9.9
担当者: 阿蘇裕樹
論文:Ubiquitin chain conformation regulates recognitionand  activity of interacting proteins
Yu Ye et al.
Nature, vol.492

 No.16 2013.9.2
担当者: 久保田俊彦
論文:Single Molecule Fluorescence under Conditions of Fast Flow
Mathew H. Horrocks et al.
Anal. Chem. 2012,84 (1),pp179-185

 No.15 2013.8.26
担当者: 吉田文
論文:A tightly regulated molecular toggle controls AAA+ disaggregase.
Yuki Oguchi et al.
Nature Structural & molecular biology, volume 19, number 12, 2012,1338-1346

 No.14 2013.8.19
担当者: 中野駿介
論文:Engineered nanostructured β-sheet peptides protect membrane proteins
Houchao Tao et al.
Nature Methods, Vol.10, No.8, 759-761

 No.13 2013.8.5
担当者:鎌形清人
論文:Single-molecule imaging of transcription factor binding to DNA in live mammalian cells.
Gebhardt JC et al.
Nat. Methods,  2013 May; 10 (5): 421-6

 No.12 2013.7.29
担当者:小井川浩之
論文:Single-molecule spectroscopy reveals photosynthetic LH2 complexes switch between emissive states
Gabriela S. Schlau-Cohen et al.
PNAS, vol.110, No.27, 10899-10903

 No.11 2013.7.22
担当者:高橋聡
論文:Crystal Structure of a GroEL-ADP complex in the relaxed allosteric state at 2.7 Å resolution
Xue Fei et al.
PNAS (2013)

 No.10 2013.7.8
担当者:久保田俊彦
論文:Gradual Disordering of the Native State on a Slow Two-State Folding Protein Monitored by Single-Molecule Fluorescence Spectroscopy and NMR
Luis Alberto Campos et al.
J. Phys. Chem. B, 24 Jun, 2013

 No.9 2013.7.1
担当者:切口理恵
論文:Surveyin Protein Structure and Function Using Bis-Arsenical Small Molecules
Rebecca A. Scheck & Alanna Schepartz
Acc. Chem. Res., 2011,44, (9), pp 654-665

 No.8 2013.6.24
担当者:伊藤優志
論文:Intrinsically Disordered p53 and its Complexes Populate Compact Conformations in the Gas Phase
Kevin Pagel et al.
Angew. Chem. Int. Ed. 2013, 52, 361-365

 No.7 2013.6.17
担当者:村田崇人
論文:Frustration in protein-DNA binding infuences conformational switching and target search kinetics
Amir Marcovitz and yaakov Levy
PNAS, vol.108, no.44, 17957-17962

 No.5 2013.6.3
担当者:吉田文
論文:Mechanical Properties of β- Catenin revealed by Single-Molecule Experiments
Alejandro Valbuena et al.
Biophysical Journal, Colume 103, Issue 8, 17 October 2012, pp1744-1752

 No.4 2013.5.27
担当者:阿蘇裕樹
論文:Site-directed nanoparticle labeling of cytochrome c
Marie-Eve Aubin-Tam et al.
PNAS, January 16, 2009

 No.3 2013.5.13
担当者:高橋聡
論文:Atomic-level description of ubiquitin folding
Stefano Piana et al.
PNAS, April 9, 2013, vol.110, no.15, 5915-5920

 No.2 2013.4.22
担当者:小井川浩之
論文:Single molecule unfolding and atretching of protein domains inside a solid-state nanopore by electric field
Kevin J. Freedman et al.
Scientific Reports 3, Article number: 1638

 No.1 2013.4.15
担当者:鎌形清人
論文:A single-molecule dissection of ligand binding to a protein with intrinsic dynamics
Eunkyung Kim et al.
Nature chemical biology