論文紹介2009

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 No.27 2010.3.19
担当者:鎌形清人
論文:Protein folding stability and dynamics imaged in a living cell
Simon Ebbinghaus et al.
Nature Methods, 2010

 No.26 2010.2.26
担当者:高橋聡
論文:Experimental evidence for a frustrated energy landscape in a three-helix-bundle protein family
Beth G. Wensley et al.
Nature, 2010,463,685-689

 No.25 2010.2.12
担当者:小井川浩之
論文:Multiple native states reveal persistent ruggedness of an RNA foldinf landscape
sergey V.Solomatin, Max Greenfeld, Steven Chu & Daniel Herschlag
Nature, 2010,463,681-686

 No.24 2010.2.1
担当者:鎌形清人
論文:The role of dynamic conformational ensembles in biomolecular recognition
David D Boehr, Ruth Nussinov, Peter E Wright
Nature Chemical Biology 5;789-796  (2009)

 No.23 2010.1.22
担当者:高橋聡
論文:Single-molecule denaturation and degradation of proteins by the AAA+ ClpXP protease
Yongdae Shin et al.
Proc Natl Acad Sci USA2009, 106, 19340-19345

 No.22 2009.12.25
担当者:小井川浩之
論文:Single-molecule spectroscopy of the temperature induced collapse of unfolded protein
Daniel Nettels et al.
Proc Natl Acad Sci USA2009, 106, 20740-20745

 No.21 2009.12.11
担当者:高橋聡
論文:Exploitation of binding energy for catalysis and design
Summer B.Thyme et al.
Nature 08508 vol 461/29 October  (2009)

 No.20 2009.11.20
担当者:鎌形清人
論文:Orientational averaging of dye molecules attached to proteins in Förster resonance energy transfer measurements: insights from a simulation study.
Allen LR, Paci E.
J Chem Phys. Aug 14;131(6):065101 (2009)

 No.19 2009.11.6
担当者:小井川浩之
論文:Direct observation of ultrafast folding and denaturedstate dynamics in single protein molecules
Hannes Neuweilera, Christopher M. Johnsona and AlanR. Fershta
Proc Natl Acad Sci USA2009, 106, 18569-18574

 No.18 2009.10.16
担当者:山森明弘
論文:Ligand Binding Mechanics of Maltose Biding Protein
Morten Berts and Matthias Rief
J.Mol.Biol.(2009)

 No.17 2009.10.9
担当者:高橋聡
論文:Direct observation of barrier-limited folding of BBL by single-molecule fluorescence resonance energy transfer.
Fang Huang, Liming Ying, and Alan R.Fersht
PNAS(2009),vol.106, 16239-16244

 No.16 2009.10.2
担当者:鎌形清人
論文:Subdomain-specific collapse of denatured staphylococcal nuclease revealed by single molecule fluorescence resonance energy transfer measurements.
Pengcheng LIu et al.
J.Phys.Chem.B,113(35),pp12030-12036 (2009)

 No.15 2009.9.11
担当者:小井川浩之
論文:Microfluidic Device for Single-Molecule Experiments with Enhanced Photostability
Edward A. Lemke et al.
J.Am.Chem.Soc. (2009)

 No.14 2009.8.28
担当者:山森明弘
論文:Mapping Transient Partial Unfolding by Protein Engineering and Native-State Proteolysis
Youngil Chang and Chiwook Park
J Mol Biol (2009) Aug12 (Epub ahead of print)

 No.13 2009.8.21
担当者:高橋聡
論文:Direct observation of an ensemble of stable collapsed states in the mechanical folding of ubiquitin
Sergi Garcia-Manyes et al.
PNAS 106,10534-10539(2009)

 No.12 2009.8.6
担当者:鎌形清人
論文:Mapping the structure and comformational movements of proteins with transition metal ion FRET
Justin W Taraska et al.
Nature Methods (2009)6, 532-537

 No.11 2009.7.24
担当者:小井川浩之
論文:Experimental determination of upper bound for ransition path time in protein folding from single-molecule photon-by-photon trajectories
Hoi Sung Chung, John M. Louis and Wiliam A.Eaton
PNAS, vol.106,11837-11844(2009)

 No.10 2009.7.17
担当者:山森明弘
論文:Continuous dissolution of structure during the unfolding of a small protein
Santosh Kumar Jhaa, Deepak Dharb, guruswamy Krishnamoorthyc, and Jayant B.Udgaonkar
PNAS,vol106,11113-11118 (2009)

 No.9 2009.7.10
担当者:高橋聡
論文:A unified model of protein dynamics
Hans Frauenfelder et al.
PNAS, March31(2009) vol.106 135126-135134

 No.8 2009.6.26
担当者:鎌形清人
論文:Single-Molecule Protein Unfolding in Solid State Nanopores
David S.Talaga and Jiali Li
JACS (2009)

 No.7 2009.6.11
担当者:山森明弘
論文:Position-Specific Incorporation of Fluorescent Non-nature Amino Acids into Maltose-Binding Protein for Detetion of Ligand Binding by FRET and Fluorescence Quenching
Issei Iijima, Tkahiro Hohsaka

担当者:高橋聡
論文:ChemBioChem 2009, 999-1006 A Reducing and oxidizing System Minimizes Photobleaching and Blinking of Fluorescent Dyes
Jan Vofelsang et al.
Angew.Chem.Int.ed. (2008) 5465-5469

 No.6 2009.5.27
担当者:小井川浩之
論文:A microfluidic mixing system for single-molecule measurements
Shawn H et al.
Rev.Sci.Instrum 80 (2009) 055105

 No.5 2009.5.14
担当者:高橋聡
論文:Minicking the folding pathway to improve homology-free protein structure prediction
Joe Debartolo et al.
Proceedings of the National Academy of Sciences (23 February 2009)

 No.4 2009.5.8
担当者:鎌形清人
論文:Continuous-flow polymerase chain reaction of single-copy DNA in microfluidic microdroplets.
Schaeli Y et al
Ana Chem.(2009) 305-306
論文:Ligand-dependent equilibrium fluctuations of single calmodulin molecules
Junker JP, Ziegler F, Reif M
Science (2009) Jan 30,323(5194): 663-667

 No.3 2009.5.1
担当者:小井川浩之
論文:Tree-dimensional, single-molecule fluorescence imaging beyond the diffraction limit by using a double-helix point spread function
Sri Rama Prasanna Pavani et al.
PNAS (2009) 2995-2999

 No.2 2009.4.24
担当者:鎌形清人
論文:Micrometer-Scale Translation and Monitoring of Individual Nanocars on Glass
Saumyakanti Khatua et al.
ACS Nano (2009)3,(2) 351-356

 No.1 2009.4.13
担当者:高橋聡
論文:Measuring internal friction of an ultrafast-folding protein
Troy Cellmer et al.
PNAS (2009) 105, 18320-18325